Posted by admin | Posted in Disease, Health Info | Posted on 13-05-2013
A Bostonian company is developing a neural stimulator whose objective to stabilize the immune system out of control in this type of diseases.
The investigation, which began a decade ago, trying to decipher the connections between the brain and immune system control, especially in the process of inflammation.
Treatment – which not yet tested in humans – constitute a breakthrough applied to inflammatory bowel diseases (IBD) such as Crohn’s disease and ulcerative colitis and in rheumatoid arthritis, autoimmune in nature all.
Brain and Immune Function
It is known that the brain has a direct connection with the spleen, the organ that contains several types of immune cells ready to launch in case of infection.
Brain and inflammation
It was shown the vagus nerve, the organ that controls in part the inflammatory process, sending signals to the brain and other organs.
Stimulation of this nerve can control or stop the fast contribution of immune cells to the site of infection course, with an effect similar to that of TNF drugs used to treat arthritis and other autoimmune diseases.
Advantages of neural stimulation
- Do not lose effectiveness over time, as with TNF treatments.
- Lack serious side effects.
- All indications are that the new treatment works better than current drugs, or simultaneously with them.
- It can be controlled easily. If the patient suffers a crisis, the device could be switched off immediately, while drugs may take days to clear.